“Grey’s Anatomy” is set in Seattle, Washington, and the vast majority of characters are said to be American. In fact, only a few main or recurring characters have had foreign accents, and none of them – Dr. Cormac Hayes (Richard Flood) and Dr. Carina DeLuca (Stefania Spampinato) – have been particularly central to the series. But don’t let the accents fool you, as many of the characters in “Grey’s Anatomy” are played by foreign actors. Dr. Callie Torres, for example, is portrayed by Mexican-born actress Sara Ramirez, who moved to the United States. at the age of eight.
“Grey’s Anatomy” also featured many Canadians in major roles. These include Sandra Oh as Dr. Cristina Yang, Catarina Scorsone as Dr. Amelia Shepherd, Scott Speedman – born in London – as Dr Nick Marsh, and Giacomo Gianniotti – born in Italy – as Dr. Andrew DeLuca. Three other cast members also had to hide their accents for the show — Camila Luddington (Dr Jo Wilson) is British, Kevin McKidd (Dr Owen Hunt) is Scottish, and Martin Henderson (Dr Nathan Riggs) is from New Zealand. “‘Grey’s’ was my first role with an American accent, and so, I’m still wrong like every day,” Luddington admitted on “Living with Kelly and Ryan” in May 2022. “It’s been 10 years now, so hopefully I’m doing a little better and in real life my accent is slowly becoming more American.”